Current and emerging therapies for neuromyelitis optica
نویسندگان
چکیده
منابع مشابه
Current and future treatment approaches for neuromyelitis optica.
Neuromyelitis optica (NMO) is an inflammatory disease of the central nervous system (CNS) characterized by severe attacks of optic neuritis and myelitis, and which, unlike multiple sclerosis (MS), commonly spares the brain in the early stages. NMO used to be considered as a special form of MS. During the past 10 years, however, the two diseases have been shown to be clearly different. NMO is a ...
متن کاملNeuromyelitis Optica
An 11-year-old girl developed sudden visual loss in her left eye, preceding subacute myelitis by 9 months. Multifocal lesions in the central nervous system were demonstrated by magnetic resonance imaging. Although unilateral blindness is unusual, the clinical findings predominantly involving the optic nerve and spinal cord were consistent with the diagnosis of neuromyelitis optica (NMO). This c...
متن کاملTreatment of neuromyelitis optica/neuromyelitis optica spectrum disorders with methotrexate
BACKGROUND To review our experience using methotrexate as a single long-term immunosuppressant (IS) therapy in neuromyelitis optica/neuromyelitis optica spectrum disorders (NMO/NMOSD). METHODS We performed a retrospective chart review of all patients with a diagnosis of NMO/NMOSD, supported by a positive NMO-IgG testing, who were treated with methotrexate. A paired sample 2 tailed t test was ...
متن کاملEpidemiology and Current Treatment of Neuromyelitis Optica: A Systematic Review.
MATERIALS AND METHODS < A systematic search was conducted of the relevant published evidence from Embase, MEDLINE, and Cochrane < Search limits were articles in English and human < Retrieved citations were screened by two independent reviewers according to inclusion criteria: < Population: NMO patients with any age Interventions: Any interventions for treatment for NMO < Outcomes: Incidence and...
متن کاملCurrent concept of neuromyelitis optica (NMO) and NMO spectrum disorders.
Neuromyelitis optica (NMO) has been described as a disease clinically characterised by severe optic neuritis (ON) and transverse myelitis (TM). Other features of NMO include female preponderance, longitudinally extensive spinal cord lesions (>3 vertebral segments), and absence of oligoclonal IgG bands . In spite of these differences from multiple sclerosis (MS), the relationship between NMO and...
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ژورنال
عنوان ژورنال: Neuroimmunology and Neuroinflammation
سال: 2016
ISSN: 2349-6142,2347-8659
DOI: 10.20517/2347-8659.2016.11